EFFECT OF Mg, Zn, Ca, AND Fe SUPPLEMENTS ON GROWTH, PROBIOTIC POTENTIAL, AND BIOFILM-FORMING CAPACITY OF LACTOBACILLUS BACTERIA

The gut microbiome is a complete set of microorganisms found in the gastrointestinal (GI) tract. Lactobacillus spp. are beneficial bacteria that normally gut. They used as type probiotic order to create homeostasis human microflora. One challenges for these ability adapt different environments survive and function properly. main research question this study was see whether specific dietary supplements (calcium citrate, iron(II)fumarate, zinc, magnesium oxide) change bacterial properties reuteri (L. reuteri) (DSM 17938) rhamnosus rhamnosus) GG (ATCC 53103). Presence affected antibiotic sensitivity tested bacteria. Results biochemical testing minimally changed. MICs have been determined well, where L. tolerated higher concentrations compared rhamnosus. Probiotic efficiency also through bile acid tolerance assays. Obtained results showed presence did not alter efficiency. According other studies form biofilm structures gut, however they very low affinity biofilms before after treatment with when vitro. Previous could be autistic-spectrum disorders. from study, patients ASD should avoid zinc capsules (as supplements) their diets, since it inhibits growth reuteri. In general, supplements, except affect on large scale.